The route serves Chester, Montgomery, and Bucks counties, passing through Lionville, Phoenixville, Trappe, Skippack, Harleysville, Souderton, and Silverdale along the way.

The route crosses into East Caln Township and becomes a divided highway again as it reaches a partial interchange with the US 30 freeway, with access to westbound US 30 and from eastbound US 30.

PA 113 widens to four lanes as it continues through suburban areas, passing to the northwest of Downingtown East High School.

The route heads to the north and gains a center left-turn lane as it runs through commercial areas in Lionville.

The road continues northeast through wooded areas with some fields and residences, passing through the community of Chester Springs and crossing Pickering Creek.

The route heads into East Pikeland Township and becomes Pike Springs Road as it continues through more rural areas with some development.

The route passes more development and fully enters Schuylkill Township before crossing into Phoenixville and coming to the PA 23 junction.

The road passes businesses and crosses under an abandoned railroad line, at which point it continues through residential areas.

[2][3] PA 113 crosses the Schuylkill River on the Black Rock Bridge into Upper Providence Township in Montgomery County and heads into fields, turning northeast onto Trappe Road.

The route passes through a mix of fields and development as it crosses the Skippack Trail and runs to the southeast of State Correctional Institution – Phoenix, heading through the community of Creamery.

[2][4] The road heads past more residential development and curves north, at which point it crosses into Lower Salford Township and becomes Harleysville Pike.

The road becomes two-lane Souderton-Harleysville Pike and passes near residential neighborhoods and farm fields before it crosses into Franconia Township.

The route runs through agricultural areas with a few homes and comes to a bridge over the Pennsylvania Turnpike Northeast Extension (I-476).

The road comes to an interchange with the PA 309 freeway, where it is briefly a divided highway, before regaining a center left-turn lane and reaching an intersection with Bethlehem Pike.

The route narrows back to two lanes and runs through a mix of farmland and woodland with some housing developments.

Farther northeast, PA 113 crosses into the borough of Silverdale and becomes Main Street, passing homes and a few businesses.

PA 113 continued northeast from Phoenixville through Collegeville and resumed along its present-day alignment in Iron Bridge.

The route ran northeast through Harleysville, Souderton, and Silverdale before it turned southeast at Kulps Corner.