The northern terminus is at PA 32 in the borough of New Hope, Bucks County, on the banks of the Delaware River.

The route passes through the urban areas of Northeast Philadelphia as Oxford Avenue, serving the Lawncrest, Burholme, and Fox Chase neighborhoods.

The route passes through more suburban development in Bucks County as Second Street Pike, running through Southampton and Richboro.

In Wrightstown Township, PA 232 enters rural areas and becomes Windy Bush Road as it heads north to New Hope.

[4] The route runs to the west of Har Nebo Cemetery and turns north through locations of homes and businesses, passing to the east of Naval Support Activity Philadelphia.

[4][5] After passing the naval facility, Oxford Avenue continues northeast at the intersection with Robbins Street/Martins Mill Road and crosses Levick Street.

[4][5] Leaving Philadelphia at the Filmore Avenue intersection, PA 232 crosses into the borough of Rockledge in Montgomery County.

[4][7] After this intersection, the road narrows back to two lanes and turns northeast into residential areas, reaching a junction with Maple Avenue.

The route widens to four lanes and passes more commercial development as it crosses PA 332 (Almshouse Road/Newtown Richboro Road).

After the Pine Lane/Pineville Road intersection, the route enters Upper Makefield Township and continues through woodland before heading into farmland.

[4][7] A short distance past the Street Road intersection, PA 232 passes into Solebury Township and crosses the Pidcock Creek.

[4][7] The road enters the borough of New Hope, where it ends at a junction with PA 32 (South Main Street).

[8] What is now PA 232 in Montgomery County was originally chartered in 1846 as the Fox Chase and Huntingdon Valley Turnpike.