Here, the route heads to the southeast and crosses the East Branch Brandywine Creek before it reaches the residential community of Glenmoore.

Past here, PA 282 continues south through forested areas along the west bank of the East Branch Brandywine Creek.

Near Springton Manor Farm, the road winds south before it makes a sharp turn to the northeast.

The route curves to the southeast and passes to the west of Marsh Creek State Park as it enters East Brandywine Township.

[2][3] Here, PA 282 runs through the community of Lyndell and continues through rural areas alongside the creek, turning to the east.

PA 282 continues south through wooded areas and crosses into Caln Township, where it passes under the US 30 freeway.

Here, PA 282 intersects Norwood Road, which heads north to a partial interchange providing access to eastbound US 30 and from westbound US 30.