The road passes through agricultural areas with some industrial development, crossing the Pennsylvania & Southern Railway's Main line.

At this point, the route passes to the east of an industrial area adjacent to the Letterkenny Army Depot.

The road continues into Southampton Township and passes through the community of Pinola, turning to the north into farmland with some woods.

The road curves to the northwest and heads into the borough of Orrstown, where it passes homes and crosses PA 533.

The road continues through farmland with some woods and homes before reaching its northern terminus at another intersection with PA 997.