The route passes through forested areas to the southeast of Bald Eagle Mountain, heading past the residential community of Nealmont.

The road heads through a mix of farmland and woods as it comes to the residential community of Warriors Mark, intersecting PA 350.

[1][4] PA 550 enters Halfmoon Township in Centre County and continues northeast through an agricultural valley with some residences.

The road passes to the north of Bellefonte Airport before heading past housing developments and running through woods, crossing Spring Creek.

[1][5] The route heads into Spring Township and becomes West Water Street, passing homes in the community of Bush Addition and turning east.

The road becomes South Water Street and passes residences and a few businesses, crossing a Nittany and Bald Eagle Railroad line and curving to the north.