The school specializes in preemptive science education with a concentration in engineering or biomedical studies.

[3] 97 percent of its 10th graders passed the AIMS Math exam (in 2009), the highest public (non-charter) school percentage in the Valley, and No.

[4] In its first year of eligibility, Bioscience earned the maximum "Excelling" Achievement Profile from the State.

The school received this award for its classrooms, collaborative learning spaces, and smooth circulation.

[9] Phoenix Union High School District received a $2.4 million small schools grant from the City of Phoenix to renovate Bioscience's existing historic McKinley building for a Bio-medical program.