It was established in June 1996 through a Memorandum of Agreement between the Municipal Government of Cabiao and the Polytechnic University of the Philippines.

The school, which was then under the PUP Open University, initially offered courses in Computer Technology and Computer Secretarial catering to unemployed adults, out-of-school youth, and high school graduates who could not pursue college education because of financial constraints.

In 2009, the school decided to stop offering vocational programs in exchange for a four-year degree, Bachelor in Elementary Education.

Vice-Mayor Ernesto S. Talens, Jr., the rest of Sangguniang Bayan members, and the Polytechnic University of the Philippines headed by Dr. Emanuel C. De Guzman, and Vice President for Branches and Campuses Dr. Joseph Mercado, the National Government funded the construction of a two-storey building with 12 classrooms.

Through a Sangguniang Bayan Resolution, PUP Cabiao Campus offered its second course, Bachelor of Science in Business Administration major in Marketing Management.