The Pony Express Bridge is a highway girder bridge over the Missouri River connecting Elwood, Kansas with St. Joseph, Missouri on U.S. Route 36 (US 36).

The truss bridge was demolished in March 1984.

The bridge is near the Pony Express stables at its eastern terminus in St. Joseph.

US 36 to Marysville, Kansas is designated the Pony Express Memorial Highway because it follows the route.

The bridge also passes over the family property of Johnny Fry, the "official" first west-bound rider of the Pony Express.