Portuense is the 11th quartiere of Rome (Italy), identified by the initials Q.XI.

The quartiere is in the southern area of the town, close to the Aurelian Walls and to the river Tiber.

To the north, Portuense borders with Rione Trastevere (R. XIII), whose border is shortly marked by Piazza di Porta Portese.

Eastward, the quartiere borders with Ostiense (Q.X) and with Europa (Q.XXXII), from which is separated by the stretch of the Tiber between Ponte dell'Industria and the Magliana Viaduct.

To the south-west, it borders with Suburbio Portuense (S. VII), whose border is marked by the Magliana Viaduct, by a short stretch of the Autostrada Roma-Fiumicino, by Via Salvatore Satta, Largo Giuseppe Petrelli, Via dell'Imbrecciato, Via Bolgheri, Via Riccardo Lombardi, and by another stretch of Via dell'Imbrecciato up to Via Portuense.