With PTS, these symptoms typically are worse after walking or standing for long periods of time and improve with resting or elevating the leg.

[1] PTS lowers a person's quality of life after DVT, specifically with regards to physical and psychological symptoms and limitations in daily activities.

This valvular incompetence combined with persistent venous obstruction from thrombus increases the pressure in veins and capillaries.

Venous hypertension induces a rupture of small superficial veins, subcutaneous hemorrhage[7] and an increase of tissue permeability.

For people hospitalized at high-risk of DVT, prevention methods may include early ambulation, use of compression stockings or electrostimulation devices, and/or anticoagulant medications.

[22][23] No treatment or prevention methods are established, but patients with upper-extremity PTS may wear a compression sleeve for persistent symptoms.