[4] The function of promyelocytes are closely linked to their differentiation into mature granulocytes, which include neutrophils, eosinophils, and basophils.
The induction phase serves to put APL in remission by reducing the number of leukemic cells and lasts approximately two months.
[11] Myelodysplastic Syndromes (MDS) are a group of disorders characterized by ineffective hematopoiesis or dysplasia changes in some myeloid lineages of the bone marrow.
[5] These associated complications may include anemia, recurrent infections, excessive bleeding and an increased risk of cancer of the bone marrow/blood cells (leukemia).
[13] Promyelocytes are essential players in the body's immune system, serving as precursors to mature granulocytes involved in host defense and inflammatory responses.
Understanding the characteristics, functions, and clinical significance of promyeloctes is crucial for the diagnosis, management, and treatment of various hematologic disorders.