It contains protein sequences databases [1][2][3][4][5][6][7] PIR was established in 1984 by the National Biomedical Research Foundation as a resource to assist researchers and customers in the identification and interpretation of protein sequence information.
[8] Winona Barker and Robert Ledley assumed leadership of the project after the death of Dayhoff in 1983.
In 1999, Cathy H. Wu joined the National Biomedical Research Foundation, and later on Georgetown University Medical Center, to head the bioinformatics efforts of PIR, and has served first as Principal Investigator and, since 2001, as Director.
[citation needed] In 2002, PIR – along with its international partners, the European Bioinformatics Institute and the Swiss Institute of Bioinformatics – were awarded a grant from NIH to create UniProt, a single worldwide database of protein sequence and function, by unifying the Protein Information Resource-Protein Sequence Database, Swiss-Prot, and TrEMBL databases.
As of 2010[update], PIR offers a wide variety of resources mainly oriented to assist the propagation and standardization of protein annotation: PIRSF,[9] iProClass, and iProLINK.