Protopopivka (Ukrainian: Протопопівка; Russian: Протопоповка) is a village in Izium Raion (district) in Kharkiv Oblast of eastern Ukraine, at about 92 kilometres (57 mi) southeast by south from the centre of Kharkiv city, on the right bank of the Siverskyi Donets river.

The village came under attack by Russian forces in June 2022, during the Russian invasion of Ukraine.

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