Pyrantel

[2] Side effects include nausea, headache, dizziness, trouble sleeping, and rash.

[7] Pyrantel pamoate acts as a depolarizing neuromuscular blocking agent, thereby causing sudden contraction, followed by paralysis, of the helminths.

This has the result of causing the worm to "lose its grip" on the intestinal wall and be passed out of the system by natural process.

Spastic (tetanic) paralyzing agents, in particular pyrantel pamoate, may induce complete intestinal obstruction in a heavy worm load.

There are a number of brands, including "Reese's Pinworm Medicine", "Pin-X", "Pin-Rid", "PYRANTRIN", "COMBANTRIN", "Anthel", "Helmintox", "Helmex", "Strongid", Konvermex, and Drontal Cat.