Radiosynthesis

Radiosynthesis is a fully automated synthesis method in which radioactive compounds are produced.

[1] Radiosynthesis is generally carried out by several nuclear interface modules, which are protected by the lead shielding and controlled by a computer semi-automatically.

In some cases, such stages of synthesis are carried out manually in order to optimize the radiochemical yield or due to the incompatibility or lack of module.

[2] Radiosynthesis modules consist of following constant components: There are also some components which are added based on the synthesis set-up such as stirrers, sterile filters, Sep-Paks™, vials, bottles, detectors etc.. Before every synthesis, the modules should be washed.

It should also be mentioned that according to Half-life of radionuclides, a relaxation time is needed between the syntheses in each module.

A fully automated radiosynthesis interface