Sieff Hospital has 310 beds and serves as a regional trauma center in the event of accidents, natural disasters, terror attacks and war.

The neonatal ICU and the Child Development Center offer health care for babies and children together with a team of medical clowns.

[citation needed] During the 2006 Lebanon War, the hospital suffered a direct rocket hit, which caused damage to the infrastructure, as well as injuring five patients, 2 doctors and two other staff members.

The center is located in a reinforced building, comprehensively addresses the needs of northern residents, and is designed to provide initial assistance in emergency events.

Under the initiative Operation Good Neighbor, 20% of wounded Syrians brought to Israel for treatment were treated in Ziv Medical Center as of July 2017.