[2] Rheumatoid neutrophilic dermatitis occurs more frequently in patients with severe, persistent seropositive arthritis; it presents clinically as erythematous papules, nodules, plaques, or lesions resembling urticaria without any accompanying symptoms.
[3][4][5] Less common conditions include annular lesions, blisters, ulcers, and vesicles.
[6][7] Skin lesions are typically symmetrical, but they can occasionally be distributed asymmetrically.
[10][11][12] Histopathological findings include normal epidermis, that may show hyperkeratosis, parakeratosis,[13] focal ulceration with scaly crust,[14] or spongiosis with intraepidermal blistering,[15] Treatments include topical steroids,[16] cyclophosphamide,[17] dapsone,[13] and hydroxychloroquine.
Although most lesions heal without leaving scars, hyperpigmentation may linger for a while.