It is located on Aristóbulo del Valle Avenue, at the junction with Callao St., north of the city centre, in the neighbourhood known as Barrio Pichincha.

The station, part of the Ferrocarril Mitre network, is currently operated by two companies, State-owned Operadora Ferroviaria (passenger services) and private Nuevo Central Argentino (NCA) (freight).

In 1908, after the merging of the BARR and the Central Argentine Railway companies, the station was set aside to handle long-distance and express services.

In June 1999 the Municipal Secretariat of Culture and Education was installed there, sharing the facilities with Tucumán Ferrocarriles and with a cargo train company (Buenos Aires al Pacífico/América Latina Logística).

[3][4] Since October 2014, State-owned company Operadora Ferroviaria Sociedad del Estado operates the Rosario Norte station as part of the passenger services from Retiro to Tucumán.