105 Avenue SW is the designated name of Highway 19 along Edmonton's southernmost city boundary between the eastern Devon town limits at the Range Road 261 road allowance and just west of the Highway 2 interchange at Nisku (Highway 2 and the interchange are not in Edmonton city limits), passing the northern edge of the Edmonton International Airport.

[3] East of Meridian (1) Street, it enters Strathcona County and continues as Township Road 512.

As part of the annexation, the strip land west of Range Road 234 (Meridian Street when it leaves Edmonton) was transferred to Leduc County.

The 1982 annexation pushed Edmonton's boundaries south of 1 Avenue, so the city adopted a quadrant system, renaming Township Road 514 to 9 Avenue SW – though Ellerslie Road has remained the preferred name by Edmontonians.

It mostly runs through residential neighbourhoods, with the exception of an area between 91 Street and Calgary Trail, sometimes called "auto row", due to all the car dealerships along the route.

East of 104 Street (Calgary Trail) the roadway goes under the name of 63 Avenue, dividing between residential and industrial areas.

Whyte (82) Avenue is part of a 40-kilometre-long (25 mi) continuous roadway that runs through Sherwood Park, Edmonton, and St. Albert that includes Wye Road, Sherwood Park Freeway, portions of University Avenue and Saskatchewan Drive, Groat Road, and St. Albert Trail.

87 Avenue was identified as the alignment of the western phase of the Valley Line of the Edmonton LRT between 159 Street and the Lewis Farms transit centre (just west of Anthony Henday Drive), serving West Edmonton Mall and the Misericordia Hospital.

A separate, short segment of 87 Avenue runs between Groat Road and 109 Street, serving the University of Alberta.

The westbound lanes occupy Stony Plain Road, while the eastbound street becomes 100 Avenue.

The roadway begins as Rowland Road at 95 Street, two blocks south of Jasper Avenue, and travels east, crossing the North Saskatchewan River along the Dawson Bridge.

After leaving the river valley, it becomes 106 Avenue at 84 Street and travels east through mature residential neighbourhoods.

The roadway begins at the 170 Street / Stony Plain Road split intersection and travels northeast to 163 Street and becomes 111 Avenue, passing a number of landmarks including the Telus World of Science, Westmount Centre, Kingsway Mall, Royal Alexandra Hospital, and Glenrose Rehabilitation Hospital.

127 Avenue is a major in north Edmonton which runs parallel CN Rail Yards opposite to Yellowhead Trail (Highway 16).

This road travels through residential, industrial and commercial areas, including shopping and entertainment centres and districts.

The road starts at Ray Gibbon Drive, in southwest St. Albert named LeClair Way.

Past there is the St. Albert Trail and Pembina commercial areas, and Castle Downs neighbourhood.

The avenue between Castle Downs Road and 97 Street forms the southern boundary of the old CFB Griesbach.

One final commercial area is located by Victoria Trail before 137 Avenue turns into 20 Street NW at Hermitage Park.

153 Avenue also exists as a small rural grid road between a dead end east of Anthony Henday Drive and 17 Street NE.

167 Avenue is the designated name of two major arterial roads in north Edmonton, separated by the Castle Downs neighbourhood.

There is also a rural section between 34 Street NW and the North Saskatchewan River, segmented by Anthony Henday Drive.

Western segment[4] Eastern segment[4] 259 Avenue is the designated name of Highway 37 along Edmonton's northernmost city boundary between Range Road 241 (50 Street NW) and Range Road 232 (33 Street NE).