Rufigallol

It occurs naturally being derived from gallic acid.

The compound is soluble in dioxane, from which it crystallizes as red needles that sublime without melting at 365 °C.

[1] It is prepared by acid-catalyzed condensation of a pair of gallic acid molecules.

[2] Rufigallol is particularly toxic to the malarial parasite Plasmodium falciparum and has a synergistic effect in combination with the antimalarial drug exifone, which has structural similarities to rufigallol.

[3] Rufigallol forms a crimson-colored complex with beryllium, aluminium, thorium, zirconium and hafnium, and this reaction has been used for the spot and spectrophotometric determination of beryllium in low concentrations.

Skeletal formula of rufigallol
Skeletal formula of rufigallol
Ball-and-stick model of rufigallol
Ball-and-stick model of rufigallol