ST8SIA4

790320452ENSG00000113532ENSMUSG00000040710Q92187Q64692NM_005668NM_175052NM_001159745NM_009183NP_005659NP_778222NP_001153217NP_033209CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase is an enzyme that in humans is encoded by the ST8SIA4 gene.

[5][6] The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1).

The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus.

Two transcript variants encoding different isoforms have been found for this gene.

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