Eliza Titus who was the first patient gave her small estate to help in creating the first hospital on McWhorter Street in Newark.

[8] In September 2021, Saint Barnabas Medical Center received a gift of $100 million from the Cooperman Family Foundation.

[9] Cooperman Barnabas Medical Center currently treats nearly 33,000 inpatients and over 95,000 adult and pediatric Emergency Department patients each year.

[13] The 56-bed Neonatal Intensive Care Unit has eight full-time neonatologists during the day, at least two newborn specialists at night, and more than 100 NICU nurses.

The division performed the first paired kidney exchange in New Jersey at Cooperman Barnabas Medical Center in 2005.

[17] The division also provides education programs such as the first live kidney transplant operation broadcast to a public audience in the UK at Dana Centre in 2007.

[21] The center also provides education and outreach programs through sponsorship from Saint Barnabas Burn Foundation which was established in 1987.

[22] The Burn Center and its staff were discussed in the book titled After the Fire: A True Story of Friendship and Survival by Robin Gaby Fisher – a Pulitzer Prize finalist in a story about the survival of the two most burned victims in the Seton Hall fire in 2000.

The department also has an accredited ACGME residency program in pathology and is a member of the Clinical and Laboratory Standards Institute.

Cooperman Barnabas Medical Center was ranked among Best Regional Hospital from U.S. News & World Report in 2021–2022.

[29] It also received high scores for its specialties from U.S. News & World Report: chronic obstructive pulmonary disease, colon cancer, congestive heart failure, diabetes and endocrinology, gastroenterology, heart attack, kidney failure, pneumonia, stroke, and urology.