[2] A part of the comarca (district) Guna Yala along the Caribbean coast of Panama, it is home to the Kuna people.

[3] Notable locations in the Archipelago are the main capital Gaigirgordub, the densely crowded island village of Carti Sugtupu, and the two keys, Cayos Limones, and Cayos Holandeses, both renowned for their clear waters.

[4] The government of Panama predicted that several islands in the archipelago could be completely submerged by 2050, causing significant displacement requiring plans to move the indigenous residents to the mainland.

The island of Carti Sugtupu is currently in the process of having its residents relocated due to frequent floods and rising sea levels, making the community the first in Panama to be displaced by climate change.

Before the arrival of Europeans, the Guna wore few clothes and decorated their bodies with colorful designs.