'Our Lady of the Sacred Heart', also known as San Giacomo degli Spagnoli and in Spanish, Santiago de los Españoles) is a Catholic church dedicated to the Virgin Mary located in Rome's Piazza Navona.

An earlier church, San Giacomo degli Spagnoli (St James of the Spanish), had been erected in the same place, on the ruins of the Stadium of Domitian, in the 12th century.

[2] In keeping with the Council of Trent's greater emphasis on the Eucharist, in 1549 Prince Philip of Spain donated funds to commission Gaspar Becerra to provide a gold tabernacle.

Commissioned as a mortuary chapel by Cardinal Jaume Serra i Cau, it was designed by Antonio da Sangallo the Younger and holds a statue of St. James by Jacopo Sansovino.

[7] Some of the paintings of the Herrera Chapel were transferred to Museu Nacional d'Art de Catalunya in Barcelona and some to Museo del Prado in Madrid.