It is located at the corner of San Marco Boulevard and Mary Street in the Southbank area of Downtown Jacksonville.

Nearby points of interest include the Museum of Science and History and Friendship Fountain Park.

As it stands at the southern approach of the Acosta Bridge, it has an unusual configuration; with its three-story interior concourse it is the highest of all the Skyway stations.

[2] Points of interest nearby include Friendship Fountain, the Museum of Science and History, and the Southbank Riverwalk.

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