[1] The restaurant serves lunch and dinner, and in 2007, Christopher Reynolds of the Los Angeles Times called Santa Fe Taqueria "a tang of Southwest flavor amid much Northwestness".

[3] The menu includes Aztec Calendar dip, blue-corn chicken, burritos, enchiladas, flautas, nachos, tacos, horchata,[4] and margaritas.

[9] In November 2015, to commemorate its 25th anniversary, Santa Fe Taqueria hosted an event with free food, drink specials, and live music, as well as activities for children such as balloon modelling and face painting.

[11] In 2020, during the COVID-19 pandemic, a parking-strip patio made of corrugated plastic walls was installed outside Sante Fe Taqueria, at a cost of approximately $6,000.

[6][14][15] Santa Fe Taqueria's horchata won in the Best Hangover Cure category of Willamette Week's 2009 "best nights" overview.