Santa Rosa is a town in Cameron County, Texas, United States.

According to the United States Census Bureau, the town has a total area of 0.77 square miles (2.0 km2), all land.

[6] As of the 2020 United States census, there were 2,450 people, 842 households, and 659 families residing in the town.

11.7% of all households were made up of individuals, and 6.2% had someone living alone who was 65 years of age or older.

The United States Postal Service operates the Santa Rosa Post Office.