[2][3] On the “Updated science-wide author databases of standardizes citation indicators”,[4] he is ranked 18th worldwide in the field of Biomedical Engineering.
In 1990, Shuguang Zhang made a serendipitous discovery of a self-assembling peptide in yeast protein Zuotin.
[15] Less widely-known, Zhang invented the QTY Code as a systematic method of rendering insoluble peptide sequences water-soluble, to facilitate biochemical research, while retaining the native conformation and functionality.
[20][21] He conceived a simple molecular QTY Code, namely Glutamine (Q), Threonine (T) and Tyrosine (Y) to systematically replace the hydrophobic amino acids Leucine (L), Valine (V), Isoleucine (I), and Phenylalanine (F) in the 7 transmembrane alpha-helices of G protein-coupled receptors (GPCRs).
This simple QTY code is a likely useful tool and has big impact for designs of water-soluble variants of previously water-insoluble and perhaps aggregated proteins, including amyloids.