Sierra de Callosa (Valencian: Serra de Callosa)[1] is a 4.6 km (3 mi) long mountain range in the Vega Baja del Segura (Valencian: Baix Segura) comarca, Valencian Community, Spain.

This range is named after the town of Callosa de Segura located at the feet of the mountains.

These conspicuous and harsh-looking massive limestone mountains rise abruptly from the low Segura River Valley floor and have some very steep cliffs.

There is very little vegetation on the arid mountain slopes and both physically and geologically the Sierra de Callosa is similar to the Sierra de Orihuela range located only 2.6 km to the west.

Smoother Sierra de Hurchillo is located 6.5 km to the south.