Sodium chlorodifluoroacetate is the organofluorine compound with the formula CF2ClCO2Na.

[2] It is a salt formed by neutralization of chlorodifluoroacetic acid with sodium hydroxide.

The compound, a white solid, is of interest as a source of difluorocarbene: This reaction is conducted in a hot solution also containing the substrate.

[2] The conversion of sodium chlorodifluoroacetate is proposed to start with decarboxylation, which generates the carbanion ClF2C−.

Thermal decomposition of sodium chlorodifluoroacetate in the presence of triphenylphosphine and an aldehyde allows for a Wittig-like reactions[3] In this case, (C6H5)3P=CF2 is proposed as an intermediate.