It is the cultural and religious center of the area's Louisiana Creole people, predominantly of French descent.

[1] The chapel is located on LA 119 near the Atahoe Plantation on the banks of the Cane River south of Natchez, Louisiana.

[3] The chapel was founded by French Creole families in the 1900s as a mission of St. Augustine Catholic Parish Church of Isle Brevelle.

During this period, St. Augustine Catholic Parish Church founded 3 other missions: St. Anne Church (Spanish Lake) (serving the Adai Caddo Indians of Louisiana), St. Joseph's Catholic Mission at Bayou Derbonne, and St. Anne Chapel at Old River.

[4] Notable Creole founding and patron families include Rachal, Longlois, Lacaze, Metoyer and Brevelle.