However, in real systems, there are minor differences in chemical environment which can lead to a distribution of resonance frequencies around the ideal.
For molecules that aren't moving, the deviation from ideal relaxation is consistent over time, and the signal can be recovered by performing a spin echo experiment.
T2*-weighted imaging can be created as a postexcitation refocused gradient echo (GRE) sequence with small flip angle.
The sequence of gradient echo T2*-weighted imaging (GRE T2*WI) requires a high uniformity of the magnetic field.
[2] T2*-weighted sequences can be used with MRI contrast, mainly ferucarbotran or superparamagnetic iron oxide (SPIO), to depict liver lesions.