Like the related TEMPO, it is used as a catalyst and chemical oxidant by virtue of being a stable aminoxyl radical.

Its major appeal over TEMPO is that it is less expensive, being produced from triacetone amine, which is itself made via the condensation of acetone and ammonia.

[3] In biochemical research, 4-hydroxy-TEMPO has been investigated as an agent for limiting reactive oxygen species.

It catalyzes the disproportionation of superoxide, facilitates hydrogen peroxide metabolism, and inhibits Fenton chemistry.

It is a promising model substance to inhibit SARS-CoV-2 RNA-dependent RNA polymerase.