2YYN, 3O33, 3O34, 3O35, 3O36, 3O37, 4YAB, 4YAD, 4YAT, 4YAX, 4YBM, 4YBS, 4YBT, 4YC9, 4ZQL880521848ENSG00000122779ENSMUSG00000029833O15164Q64127NM_003852NM_015905NM_001272064NM_001272076NM_145076NP_003843NP_056989NP_001258993NP_001259005NP_659542Tripartite motif-containing 24 (TRIM24) also known as transcriptional intermediary factor 1α (TIF1α) is a protein that, in humans, is encoded by the TRIM24 gene.

[5][6][7] The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors.

The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors.

Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

[6][11] This article incorporates text from the United States National Library of Medicine, which is in the public domain.