Tagliolo Monferrato is a comune (municipality) in the Province of Alessandria in the Italian region Piedmont, located about 90 kilometres (56 mi) southeast of Turin and about 30 kilometres (19 mi) south of Alessandria.

As of 31 December 2004, it had a population of 1,499 and an area of 25.9 square kilometres (10.0 sq mi).

[3] The municipality of Tagliolo Monferrato contains the frazioni (subdivisions, mainly villages and hamlets) Cherli, Grossi, Varo, Pessino, Caraffa, Gambina and Mongiardino.

Tagliolo Monferrato borders the following municipalities: Belforte Monferrato, Bosio, Casaleggio Boiro, Lerma, Ovada, Rossiglione, and Silvano d'Orba.

This article on a location in the Province of Alessandria is a stub.