Motivated by the urgency of need to serve the youth of growing Taguig City, the Local Government Administration came up with Ordinance No.

29 Series of 2004 "An Ordinance Establishing the Pamantasan ng Taguig and Appropriating Funds Thereof."

Meanwhile, undergraduate classes were held in high schools and elementary campuses in Taguig, lent to the growing management of TCU.

In 2006, General Ricardo Papa Sr. Memorial High School offered some rooms for free.

It paved the way to the development of the Master of Arts in Educational Management, while holding classes in a secluded and secured room at Sunshine Mall Taguig.

School year 2009-2010 reflected the metamorphosis of youthful Taguig City University, because in June all classes from undergraduate to graduate programs started to be held at the new main building of TCU; the rest became part of history.

On TCU's first year of operation, 2006–2007, the university was under the stewardship of the vice president for Academic Affairs, Tess Umali.

With the passage of the Republic Act 10931, or the free tuition law of 2017, TCU officially became tuition-free.