[3] Enderun Colleges was established in 2005 by a group of business and community leaders, Jack Tuason, Javier Infante, and John Suits, who previously founded Ambergris Solutions, now known as TELUS International Philippines.

[4][5] The pioneering founders were later joined by Daniel Perez, an alumnus of Les Roches International School of Hotel Management, along with prominent business leaders Jean-Henri Lhuillier of PJ Lhuillier, Inc., Rosanna Fores of TELUS International Philippines, John Tiu of JTKC Group of Companies, Alvin Lao of Chemrez Technologies, and senior US-based executives from Hyatt Corporation.

[4] In 2006, the college launched with the accreditation of the Philippine Commission on Higher Education (CHED), with Dr. Lorraine Villanueva as the founding Dean.

There were 80 students enrolled in the college's only degree at the time: International Hospitality Management, with specialization in Hotel Administration or Culinary Arts.

[13][15][16][17] In 2017, Le Pensuer, Inc., an American business consulting company, acquired the 20% holdings of A. Soriano Corporation (ANSCOR) in Enderun.

[19] Built on nearly 2 hectares in the McKinley Hill area of Bonifacio Global City, the campus currently has four buildings—the enderun tent which is used for private parties and events, the Hotel Administration Center, the College of Business and Entrepreneurship, and Ducasse Institute Philippines.

[21][22] Enderun offers a Bachelor of Science in International Hospitality Management with specialization in Hotel Administration or Culinary Arts.

It offers the opportunity to customize the student's junior and senior year to take advantage of the school's culinary arts and restaurant management programs.

Upon completion of a three-course track from Thunderbird Online, students will receive an Executive Certificate in Global Leadership after graduation.