[1] He played running back, wide receiver, and cornerback, and also returned kicks and punts.

At the 2011 IHSA State Championships, he placed fourth in the 100m, at 10.86, and took second in the long jump, getting a personal-best mark of 7.16 meters.

He chose Indiana over scholarship offers from Georgia Tech, Minnesota, and Michigan State.

[5] Sources: Coleman attended and played college football for Indiana University from 2012 to 2014 under head coach Kevin Wilson.

[19] On November 25, Coleman and fellow Big Ten Conference running backs Melvin Gordon (Wisconsin) and Ameer Abdullah (Nebraska) were named the three finalists for the Doak Walker Award.

[25][26] On December 29, 2014, Coleman announced that he would forgo his senior season and enter the 2015 NFL draft.

[33][34] On September 8, 2015, due to the injury of Devonta Freeman, Coleman was named the Falcons feature running back to start the season.

[35] On September 14, 2015, Coleman made his NFL debut, running for 80 yards on a season-high 20 carries against the Philadelphia Eagles on Monday Night Football.

[38] On November 29, 2015, Coleman ran for a season-high 110 yards on 18 carries against the Minnesota Vikings, his first 100-yard game of his career.

[41] During the season opener, Coleman caught five passes for 95 yards in a 31–24 loss against the Tampa Bay Buccaneers.

[48][49] On February 5, 2017, Coleman scored a six-yard receiving touchdown in the third quarter of Super Bowl LI against the New England Patriots.

[52] During a Week 2 34–23 victory over the Packers, Coleman had six carries for 42 yards and a three-yard receiving touchdown in the first game in the new Mercedes-Benz Stadium.

[59] He was named the starter the rest of the season in Week 6 after a season-ending injury to Devonta Freeman.

[63][64] During the season-opener against the Buccaneers, Coleman rushed for 23 yards on six carries but suffered a high-ankle sprain that kept him sidelined for four weeks.

[70] In the Divisional Round of the playoffs against the Vikings, Coleman rushed 22 times for 105 yards and two touchdowns during the 27–10 victory.

[71] In the NFC Championship against the Packers, he had six carries for 21 yards, but left the game early with a shoulder injury.

[72][73] In the Super Bowl, Coleman recorded five carries for 28 yards and caught a three-yard reception, but the 49ers lost to the Kansas City Chiefs by a score of 31–20.