The route was originally designated in 1930 between Pampa and Wheeler, but was extended both west (replacing State Highway 209 from Pampa to Borger) and east to its current termini in 1938.

On December 24, 1935, a highway was temporarily designated from Wheeler to the Oklahoma state line.

[2] On June 21, 1938, the route was extended west to Borger, replacing SH 209.

The route was also designated north concurrent with then-State Highway 117 until they reached Stinnett, where the route would be extended west via Dumas to Hartley, replacing SH 178.

The route was created in 1939 as Loop 79, which was redesignated Business SH 152-B on June 21, 1990.