It was serialized in Sanrio's shōjo manga magazine Lyrica [ja] from November 1976 to March 1979 and collected in two volumes.

The West Wind is commanded to take Unico through space and time, to the Hill of Oblivion with no memories of Psyche where he will wander forever.

The West Wind takes pity on Unico, and decides to pass over the Hill of Oblivion and send him to different places in different time periods.

Unico befriends the people he meets there and helps them achieve happiness, before the West Wind takes him away once more to avoid detection from Venus, wiping his memories in the process.

However, the gods feel that punishment may be too harsh and instead choose to send the West Wind to capture Unico and take him to the Hill of Oblivion.

In the reboot series, Unicorns were born from "life's secret undercurrent", and the friendship between Unico and Psyche sends an inspiring force between people throughout time, angering Venus.

After a long time of transporting Unico to different places, the West Wind follows a whisper promising to break the cycle, sending the unicorn to the modern day.

On September 20, 2023, Scholastic Corporation announced that the manga series will be published by their Graphix imprint banner with the first volume, a reimaging of the chapter "The Cat in the Broomstick" was released August 6, 2024 in the United States.

[4][5] Tezuka Productions and Scholastic also announced the series to be expanded to 4 volumes alongside an activity book and handbooks to accompany them.

An animated music video called "Song of Unico" based on Volume 1 was uploaded on September 9, 2024 in both English[12] and Japanese.

[13] A second volume titled Unico: Hunted based on the chapter "Black Rain and White Feathers" was announced at San Diego Comic-Con 2024 and has a release set for June 3, 2025.

This musical film, narrated by singer–songwriter Iruka, directed by Toshio Hirata, and written by Masaki Tsuji, with animation by Yoshiaki Kawajiri, adapts the chapters "Unico and Solitude" and "The Cat in the Broomstick".

Beezle realizes how lonely he is and risks his life to save Unico, returning his horn and turning him into a mighty winged unicorn that takes them to dry land.

Moribi Murano (often miscredited as "Mami Sugino") directed the second movie, titled Maho no Shima e (ユニコ 魔法の島へ, To the Magic Island) in Japanese and Unico in the Island of Magic in English, which was released to Japanese theaters on July 16, 1983, five days before the release of the first Barefoot Gen movie, which used many of the same production staff.

It was also released direct-to-video in the United States by RCA Columbia Pictures Home Video on November 10, 1983, and on Canal de las Estrellas in Mexico on January 30, 1988.

Later, Unico meets a kind-hearted young girl named Cheri (also spelled "Cherry", voiced by Sumi Shimamoto).

Cheri's older brother, Toby (in Japanese, "Torubi", voiced by Shuichi Ikeda), is working for the evil Lord Kuruku (in Japanese, "Kukuruku"), who plans to turn all living creatures, animals and people alike, into unusual zombie-like beings called "Living Puppets" to be his slaves.

Seeking advice from the Trojan Horse, Unico and Cheri learn that Kuruku is a puppet who was mistreated by his owners and discarded.

The 1981 and 1983 theatrical films were dubbed into English and received North American exposure through VHS releases in the mid-1980s and airings on the Disney Channel.

Writing for Anime News Network, Shaenon K. Garrity called Unico "a good-looking manga", saying the "artwork looks like a comic-book version of the prettiest Disney movie never made".