University Avenue is a downtown street in Lewisburg, Pennsylvania, United States.

It was the original main access road to the University at Lewisburg (Bucknell University today), located on the northern side of the campus, and still leads to its former main entrance, punctuated by the 1905 Memorial Gateway.

[3] Several fraternity and sorority buildings stand on University Avenue, including Kappa Sigma and Phi Gamma Delta, while President's House is located at the intersection with Loomis Street, across from Lowry House (former home of hymn-writer Robert Lowry).

[4] The Union County Industrial Railroad passes beside both of these buildings as it crosses University Avenue.

It empties into the West Branch Susquehanna River a short distance to the southeast.