Massachusetts Route 140 passes through the CDP, leading northwest 12 miles (19 km) to Shrewsbury and southeast 14 miles (23 km) to Franklin.

According to the United States Census Bureau, the CDP has a total area of 6.6 km2 (2.6 mi2), of which 6.4 km2 (2.5 mi2) is land and 0.2 km2 (0.1 mi2) (2.73%) is water.

It is also home to the town's historic Knowlton Hat Factory, now repurposed as the Millhaus Apartments.

As of the census[3] of 2000, there were 2,326 people, 914 households, and 617 families residing in the CDP, at the time listed as "Upton-West Upton".

27.9% of all households were made up of individuals, and 13.0% had someone living alone who was 65 years of age or older.