Uranyl zinc acetate (ZnUO2(CH3COO)4) is a compound of uranium.

Uranyl zinc acetate is used as a laboratory reagent in the determination of sodium concentrations of solutions using a method of quantitatively precipitating sodium with uranyl zinc acetate and gravimetrically determining the sodium as uranyl zinc sodium acetate, (UO2)3ZnNa(CH3CO2)9·6H2O.

[1][2] This method was important to determine Na in urine for diagnostic purposes.

Zinc uranyl acetate is sometimes called "sodium reagent" since pale yellow NaZn(UO2)3(C2H3O2)9 is one of the very few insoluble sodium compounds.

[citation needed] Uranyl zinc acetate has been used as a catalyst for the demethoxylation of toluene-2,4-dicarbamate into toluene-2,4-diisocyanate (TDI).