[17] This was driven by her playing the online multiplayer social deduction game Among Us and collaborating with popular streamers like Disguised Toast, Sykkuno, Pokimane, PewDiePie, and Cr1TiKaL,[17] in addition to public figures like politician Alexandria Ocasio-Cortez, musician Lil Nas X, and television personality Jimmy Fallon.

[19] On April 7, 2021, Hofstetter and CouRageJD joined the ownership group of 100 Thieves, alongside Dan Gilbert, Scooter Braun, Drake, and its founder, Nadeshot.

[20] Throughout 2021, she made appearances in music videos for "DayWalker" by Machine Gun Kelly featuring Corpse Husband,[21] as well as "Build a Bitch" and "Inferno" by Bella Poarch.

[28] On March 11, 2023, she co-hosted the second annual Streamer Awards alongside the event's creator, QTCinderella; the ceremony averaged 425,000 live concurrent viewers.

[35] In September 2024, Hofstetter founded the media company Hihi Studios to "develop and produce IP for graphic novels, TV and film projects with a specific emphasis on anime-inspired content.

[42][43] On April 6, 2021, Hofstetter participated in an Among Us charity livestream held by The Tonight Show host Jimmy Fallon with several notable celebrities such as Gaten Matarazzo and Noah Schnapp of Stranger Things, American hip-hop band The Roots members Questlove, Black Thought, and Captain Kirk Douglas, and fellow streamers and YouTubers Sykkuno and Corpse Husband.

[44] In June 2022, Hofstetter participated in a Minecraft charity tournament held by the MC Championship with several other creators to raise money for The Trevor Project.

[46][47] In December 2022, Hofstetter participated in "Thankmas", an annual charity livestream event hosted by YouTuber jacksepticeye, to raise money for World Central Kitchen.

The brand, primarily geared towards gamers and those who put in heavy screen time, claimed that users are susceptible to skin damage caused by prolonged exposure to blue light and that their products protect against it.

RFLCT received backlash due to insufficient evidence supporting the claim;[50][51] according to Kathleen Suozzi, the director of the aesthetic dermatology program at Yale University, unless someone was already prone to melasma or hyperpigmentation, they were unlikely to suffer any consequence of sitting in front of a screen for long periods of time.

A statement on the website read: "While we believe in the formulations created, after further reflection, have decided to move forward on new paths, effectively terminating the RFLCT brand.

[31] From April 2023 to July 2024, she lived with fellow streamers Leslie "Fuslie" Fu, Miyoung "Kkatamina" Kim, and Christina "TinaKitten" Kenyan, collectively known as "The Roomies".