Wildhorse Creek is a tributary of Alvord Lake in Harney County in the U.S. state of Oregon.

[4] Near the headwaters, the creek enters and exits Wildhorse Lake, which lies in a hanging valley.

The upper 7-mile (11 km) of the creek, including Wildhorse Lake, are part of the National Wild and Scenic Rivers System.

[5] Designated "wild", the creek's watershed is home to mule deer, elk, bighorn sheep and pronghorn.

[5] Wildhorse Lake, covering about 20 acres (8 ha), supports populations of Lahontan cutthroat trout, which spawn in the creek.