Fischer worked early in his career with blues and R&B musicians, playing in the 1950s with Ray Charles, Guitar Slim, Big Joe Turner, and Muddy Waters.
After briefly returning to Xavier as an instructor, he continued his education with non-degree coursework (including experimentation with early synthesizers) at the Vienna Academy of Music and Performance in 1965–66.
Comprising his band were guitarists Hugh McCracken and Eric Weissberg, Ron Carter on electric bass, Billy Cobham on drums/percussion, and Bill Robinson on vocals.
Fischer also composed and directed the keyboard elements for the Moog, which were realized at Walter Sear Electronic Music Studio in New York.
[1] On the Spanish label Herri Gogoa, Fischer released Akelarre Sorta, a collection of psych-soul treatments of Basque folk idioms.