Located in western Saitama Prefecture to the north of Mount Bukō, Yokoze is in the southeast portion of the Chichibu Plains.

Saitama Prefecture Yokoze has a humid subtropical climate (Köppen Cfa) characterized by warm summers and cool winters with light to no snowfall.

The village of Yokoze was created within Chichibu District, Saitama with the establishment of the modern municipalities system on April 1, 1889.

Yokoze, together with the towns of Higashichichibu, Minano, Nagatoro and Ogano, contributes one member to the Saitama Prefectural Assembly.

In terms of national politics, the town is part of Saitama 11th district of the lower house of the Diet of Japan.