1,3,5-Tribromobenzene is an aryl bromide and isomer of tribromobenzene, also known as sym-tribromobenzene.

[2] Brominating aniline with elemental bromine gives 2,4,6-tribromoaniline.

This is then diazotized, then reacted with ethanol to replace the diazonium group with hydrogen, forming 1,3,5-tribromobenzene.

[3] It has also been prepared by these methods:[3] 1,3,5-Tribromobenzene is a precursor to C3-symmetric molecules.

It undergoes a Suzuki reaction with three equivalents of 4-formylphenylboronic acid to form 1,3,5-tris(4-formylphenyl)benzene (TFPB), a monomer for covalent organic frameworks.