On September 25, it made a second landfall just south of Tampico, Tamaulipas with winds at around 110 mph (180 km/h), and it quickly dissipated over land.

It moved west-northwestward through the Lesser Antilles, passing about 14 mi (23 km) south of Grenada; however, the system was very weak, and the island reported east winds of only 12 mph (19 km/h).

Early on September 22, it passed about 50 mi (80 km)[nb 2] south of Cozumel before making landfall on the Yucatán Peninsula.

The cyclone rapidly weakened while crossing the Yucatán peninsula, and on September 23 it emerged into the Gulf of Mexico with winds of 65 mph (105 km/h).

At around 0000 UTC on September 25, the hurricane made its final landfall just south of Tampico, Tamaulipas with winds of 110 mph (180 km/h); this was based on a ship in the eye reporting a pressure of 960 mbar (28 inHg).

[3] High winds cut power lines and blew off or heavily damaged the roofs of half of the city's houses.

[7] Majority of the damage was to poorly constructed houses,[8] although a large hospital in Tampico was also destroyed,[12] killing 87 people.

[10] Outside of the city, the hurricane increased levels along the Pánuco and Tamesí rivers,[11] which remained above flood stage for several days.

[14] West of Tampico, the hurricane flooded the entire city of Cárdenas, San Luis Potosí, killing 20 and injuring 200 people.

[12] Initial news reports suggested a death toll of up to 5,000 people, and the storm was considered "the greatest disaster in recent Mexican history".

[7] Two days after the storm dissipated, the death toll was set at 54, with 850 people injured and potentially thousands that were buried.

[10] After the storm dissipated, doctors and nurses traveled to the city to assist in the aftermath, while trains carried food and water.

[7] A train from Monterrey to Tampico carried food, medicine, and soldiers to assist in rebuilding, but was delayed by ongoing flooding.