The last year cup holder SKA Kiev was knocked out of the competition by Mayak Kharkiv already in the second round.
Polissya Zhytomyr entered the competition in the quarterfinals receiving bye past two rounds.
The competition was conducted by the clubs of 1991 Soviet Lower Second League, Zone 1 only.
Many Ukrainian professional teams (18) in higher tiers of the Soviet football league pyramid did not take part in the competition.
[1] The following clubs received bye for the next round: Podillya Khmelnytskyi, Kryvbas Kryvyi Rih, Dynamo Bila Tserkva, Kolos Nikopol, Dnipro Cherkasy, Shakhtar Pavlohrad, SKA Kiev, Mayak Kharkiv, Zirka Kirovohrad, Desna Chernihiv.